Abstract: In recent decades, the increased temperatures reported in Europe and in the Mediterranean basin represent one of the clearest footprints of climate change along with increased frequency of heat waves. These climate modifications put the environment and human activities under strong pressure with a resulting need for designing new adaptation and mitigation strategies. The climate change challenge is unprecedented for humanity and is recognized as a priority topic for future research. Changes in the way we think and behave are critical challenges at the global and regional levels.