Abstract: Centre for Regionalchange in the Earth System (CRES, cres-centre.net) is funded by the DanishStrategic Research Council for the period 2009-2014 and is coordinated by theDanish Meteorological Institute. CRES has established a coordinated researcheffort aiming to improve societal preparedness for climate change, inparticular for Denmark. The overall objective of CRES is to extend knowledge ofand reduce the uncertainties surrounding regional climate change and itsimpacts and thereby support future climate change adaptation and mitigationpolicies. Some of the objectives that also have large synergies with theeffects in the CropM theme of MACSUR are a) to reduce uncertainty surroundingregional climate change and its impacts for the period 2020-2050 by improvingmodel formulation and process understanding; b) identify key changes andtipping points in the regional hydrological system, agriculture, freshwater andestuarine ecosystems caused by changes in seasonality, dynamics and extremeevents of precipitation, droughts, heat waves and sea level rise; c) quantifyconfidence and uncertainties in predictions of future regional climate and itsimpacts, by improving the statistical methodology and substance and byintegrating interdisciplinary risk analyses; d) interpret these results inrelation to risk management approaches for climate change adaptation andmitigation. Studies in CRES of particular interest to MACSUR include a)Estimation on generic crop model uncertainties in projection of climate changeimpacts on wheat year, b) Assessment of uncertainties in projected effects onwater balance, crop productivity and nitrate leaching of changes in land use,climate and assessment models.