Abstract: Grassland models are valuable tools to test hypotheses on grassland ecosystem functioning. In the frame of FACCE MACSUR LiveM, a model intercomparison was conducted using a dataset from an observational and experimental network of nine multi-year grassland sites spread across Europe (France, Italy, Germany, Switzerland, The Netherlands, and United Kingdom) and Israel, and a suite of nine models to understand grassland functioning in the region. Grassland-specific approaches were compared to approaches mainly conceived to simulate crops and plant functional types. Model evaluation against actual measurements was performed before and after model calibration. The calibrated models were used to analyze their sensitivity to independent variations of temperature, precipitation and [CO2]. The results show to which extent calibration can accommodate model discrepancies. The sensitivity of simulated gross primary production to [CO2] and temperature is an important outcome, considering the fundamental effect of rising temperature and [CO2] on the C cycling of terrestrial ecosystems in the Euro-Mediterranean region. Overall, alternative models exhibit a different sensitivity to climate change factors, with different performances over different conditions. Explained by the basic processes of each model and also induced by different calibration methods, this difference is indicative that more models can be complementary and deliver greater insights than if they were applied individually. No Label