Abstract: This special issue includes a sub-set of papers developed in the context of the three-years (2013-16) research project “IC-FAR – Linking long term observatories with crop system modelling for a better understanding of climate change impact and adaptation strategies for Italian cropping systems” (www.icfar.it), funded by the Italian Ministry of Education, University and Research. IC-FAR collects the legacy of some three-four generations of researchers, members of the Italian Society of Agronomy, that from the 1960ies onward established long term agro-ecosystem experiments (LTAE) in various Italian locations, to address a wide range of agronomy research questions. A lot of the results from these LTAE were not yet published or were published as grey literature or in Italian and almost always as a single-site, single-experiment outcome.